The results of a new study in the New England Journal of Medicine show that men who take testosterone boosters can increase their testosterone levels by as much as fivefold.
The researchers found that men taking testosterone boosters who had previously taken a statin, like a statmedra or a cholesterol-lowering medication, did not gain enough testosterone to increase their men’s testosterone levels.
The study, which also included 6,000 men, looked at the testosterone levels of 6,600 men and found that those taking testosterone supplements did not increase their levels of testosterone by nearly as much.
“In this study, we found that testosterone boosters do not appear to increase testosterone in men who have taken statins and are taking statmeds,” said study author Eric J. Ollis, MD, of Brigham and Women’s Hospital, Boston, Massachusetts.
“Instead, we observed a dose-dependent dose-response relationship, where a modest dose increase is sufficient to increase the rate of testosterone increase, but a high dose increase can cause men to lose more testosterone than they gain.”
The findings of the study, conducted by the researchers at Brigham and Womens Hospital, suggest that men with existing prostate cancer who take high doses of testosterone boosters could be at risk for worsening the disease.
“For the first time, we have a study that shows that men can experience testosterone boost without getting cancer,” said lead author Dr. Jeffrey L. Trenberth, MD.
“We are very interested in finding out how to make testosterone boosters work in the most effective way to help men who already have prostate cancer.”
The study looked at men who were diagnosed with prostate cancer between 2011 and 2014.
It examined testosterone levels in the men and their patients as well as their medical history, and then compared the testosterone gains made with statmeda or cholesterol-control medication.
Trenbert said that while the men in the study were not necessarily “trying to get cancer,” they were looking to increase hormone levels to help them fight the disease in the meantime.
“What we’re doing here is looking at whether or not the testosterone boosters that we’re prescribing to men could be the right choice for men,” he said.
The study found that in men with prostate-specific antigen (PSA) testing positive for prostate cancer, men taking the testosterone supplements had an average increase in testosterone of 0.2% on average, while those who did not take testosterone supplements also experienced a 0.7% increase in their testosterone.
This means that taking the hormone boosters could theoretically increase testosterone levels enough to potentially boost the rate at which a man could increase testosterone to help fight prostate cancer.
The men in this study were divided into two groups.
The first group took a testosterone booster for two months and then stopped taking it.
The second group took the testosterone booster and then continued taking the statmed.
After taking the test and seeing their testosterone level rise, the men who took testosterone boosters were more likely to have a significant increase in the number of testosterone-boosting tests, which is likely because testosterone is a steroid hormone.
Ollis said that the researchers believe that the hormone boosters could potentially be helpful to men who do not want to take statmed drugs to help control their prostate cancer and want to continue taking testosterone to combat the disease later in life.
“This is a very interesting finding,” he told ABC News.
“It shows that the men are not just using these hormones as a means to combat prostate cancer but also to increase testicular cancer risk.”
Trenbrenth said that he hopes that this study will help scientists identify other ways to increase men’s natural testosterone levels, but added that the results should not be interpreted as indicating that testosterone can be used to treat prostate cancer or as a cure.
“The results of this study suggest that the testosterone supplement is not a cure for prostate disease,” he added.
“But it is important that men not use testosterone supplements to treat or prevent prostate cancer if they are taking a statmeasure, such as a statMED or statmedRA.”
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The testosterone boosters are now available for purchase from the National Institutes of Health’s Clinicaltrials.gov site, but there is currently no evidence that they can treat or reverse the progression of prostate cancer in men.