The testosterone hormone, also known as testosterone, is a powerful hormone that is produced naturally in the body and plays an important role in sexual development.
In fact, the majority of men can be identified by their size and weight and are usually found to have higher levels of the hormone in their body than women.
Testosterone can also affect the appearance of the face, hair and nails.
Testothenes can also play a role in the development of the brain and the cardiovascular system, and the hormone is associated with increased longevity.
But, in recent years, research has been suggesting that men who have low testosterone levels may also suffer from other health problems, such as depression and osteoporosis.
And in an important new study, researchers found that men with low testosterone had significantly higher levels than average of the following:1) High blood pressure2) Diabetes3) High cholesterol4) Heart disease5) Diabetes-related cancer6) High triglycerides7) High levels of inflammation8) High LDL cholesterol9) High insulin levels10) High HDL cholesterolIn a new study published in the journal Diabetes, researchers from the University of Copenhagen found that low testosterone was associated with a significantly higher risk of heart disease, high triglycerides, and insulin resistance.
And even though men who were in the lowest testosterone group had lower levels of HDL cholesterol, the study also found that those with low levels of testosterone had higher levels for these markers.
So, what causes low testosterone?
The answer, according to Dr. Lars Fjellström, a professor at the University, is that testosterone is metabolized differently in men than women, so it may be produced in a different way.
But in a study of over 10,000 men, he found that the biggest contributor to testosterone levels was a genetic mutation that results in a shorter-chain amino acid (TCA) in the male body called DHT, which causes a deficiency in DHT receptors.
This leads to lower levels and increases the need for testosterone in the brain.
The same mutation also causes a lack of the testosterone-binding protein (TBP), which helps to regulate the amount of TCA and its subsequent conversion into testosterone.
So, the more DHT you have, the lower the level of testosterone.
But Fjells study also showed that the same mutation was also associated with higher levels in people with prostate cancer.
And, even though the study looked at men, the same mutations also caused increased risks for heart disease and type 2 diabetes.
Fjells team found that it was possible to identify individuals who were genetically predisposed to lower testosterone levels by looking at the amount and type of DHT in their blood.
The researchers then identified the people who had the highest and lowest levels of DBT, which is a marker for testosterone deficiency.
In the men with DBT levels of less than 50 ng/mL, for example, the testosterone levels were lower than average.
But the men in the highest testosterone group also had lower testosterone than average, and this was not a case of a low testosterone group just lacking DHT.
In addition, the researchers found evidence that some men with this genetic mutation may also have other health issues.
In this group, testosterone levels could be higher than average for some people.
And this may also be linked to other health conditions, such a high triglyceride level, high LDL cholesterol, and elevated blood pressure.
“The genetic risk factors for low testosterone are different for each individual, so we don’t know why some people with the mutation and others don’t have it may have these health problems,” said Fjelts team leader Dr. Johanna Lagerberg-Fjellstorff, who also serves as a professor of medicine and epidemiology at the Department of Medicine and Epidemiology at Copenhagen University Hospital.
“This is a very promising result, but we need more information about the mechanisms that underlie the effects of the genetic mutations.”
While this study is promising, Fjels team is currently looking into how genetic factors affect the way men metabolize testosterone.
They plan to conduct further studies in other populations and, ultimately, they hope to develop a drug that would treat testosterone deficiency and other health effects.